19 October 2025
: Case report 
Escherichia coli-Induced Aortitis and Aortic Perforation: A Case Study and Literature Review
Challenging differential diagnosis, Diagnostic / therapeutic accidents, Unusual setting of medical care, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology
Hiba Abdelkareem ABCDEF 1, Saif Aldeen Jabarin ABEF 1, Ahmad Farhoud B 2, Yuval Schwartz AD 1, Ilya Goldin BDE 3, Gabriel Munter ADEG 1,2*DOI: 10.12659/AJCR.949202
Am J Case Rep 2025; 26:e949202
Table 1 Initial laboratory investigations supporting the diagnosis of Escherichia coli aortitis.
| Laboratory parameter | Results | Reference range |
|---|---|---|
| White blood cell count (WBC) | 13 900 cells/μL | 3600–10 000 cells/μL |
| C-reactive protein (CRP) | 20.5 mg/dL | <0.5 mg/dL |
| Erythrocyte sedimentation rate (ESR) | 119 mm/h | 0–20 mm/h |
| Creatinine | 0.93 mg/dL | 0.66–1.25 mg/dL |
| Alkaline phosphatase | 123 IU/L | 38–150 IU/L |
| Aspartate aminotransferase (AST) | 40 IU/L | 17–59 IU/L |
| Alanine aminotransferase (ALT) | 11 IU/L | 21–70 IU/L |
| Gamma-glutamyl transferase (GGT) | 146 IU/L | 15–73 IU/L |
| Lactate dehydrogenase (LDH) | 296 IU/L | 125–220 IU/L |
| Bilirubin | <0.5 mg/dL | 0.2–1.3 mg/dL |
| Blood cultures | Negative | – |