09 November 2025
: Case report 
Atypical Presentation of Seronegative Autoimmune Encephalitis as Refractory Status Epilepticus: A Case Report
Challenging differential diagnosis, Rare disease
Bayan Alalawi ABEF 1*, Feras Beitar ABEF 1, Salma Alalawi ABEF 1, Hamza Alhariri AE 2DOI: 10.12659/AJCR.949451
Am J Case Rep 2025; 26:e949451
Table 3 Laboratory testing for autoimmune disease.
| Autoimmune testing | Blood | Cerebrospinal fluid | Range |
|---|---|---|---|
| Anti-Ro (anti-Sjögren’s-syndrome-related antigen A) | |||
| Anti-La (anti-Sjögren’s-syndrome-related antigen B) | |||
| Anti-SS-A | |||
| Anti-SS-B | |||
| Anti-SS-SM | |||
| Anti-dsDNA | |||
| ANA | Negative | Negative | |
| Immunoglobulin G (IgG) | |||
| Immunoglobulin A (IgA) | 15.3 | ~2 mg/L | |
| Immunoglobulin M (IgM) | 2.05 | ~2 mg/L | |
| Oligoclonal bands | Negative | Negative | Negative |
| Glutamate receptor abs (NMDA type) | |||
| Ri abs (IFT) | – | ||
| Yo abs (Purkinje cells) (IFT) | – | ||
| Protein C activity | |||
| Protein S antigen, free | |||
| Lupus anticoagulants 1 screen (Dutra ET AL. (2 p1)) | |||
| Lupus anticoagulants 2 confirm (LA2) | |||
| Ratio (LA1/LA2) | |||
| Anticardiolipin IgA | |||
| Anticardiolipin IgM | |||
| Anticardiolipin IgG |