Nocardia farcinica Brain Abscess in a Glucocorticoid-Treated Patient with Giant-Cell Arteritis: A Case Report

23 November 2025 : Case report Japan

Adverse events of drug therapy, Rare coexistence of disease or pathology

Simon Valenti

^{ABCDEF 1}, Masahiro Kogami

^{DE 2*}, Mai Suzuki^{CDE 1}, Toshio Naito

^{E 1}, Naoto Tamura^{E 2}

DOI: 10.12659/AJCR.949616

Am J Case Rep 2025; 26:e949616

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Table 2 Reported cases of Nocardia infection in patients with giant-cell arteritis.

References	Site of infection	Nocardia species	Interval from giant-cell arteritis diagnosis to nocardiosis onset	Immunosuppressive therapy at the time of nocardiosis
[]¹⁵	Refractory glabellar ulcer	spp.	3 weeks	Prednisolone 40 mg/day
[]¹⁶	Systemic abscesses involving the brain		8 months	Prednisolone 25 mg/day
[]¹⁷	Pneumonia		1 month	Corticosteroid (1 mg/kg/day)
[]¹⁸	Disseminated abscesses including the brain		5 weeks	3 pulses of intravenous methylprednisolone (dose not specified)
[]²⁴	Cutaneous and pulmonary abscesses	spp.	1 month	Methylprednisolone and azathioprine (dose not specified)
[]²⁵	Lung abscess		3 to 4 months	High-dose corticosteroids (dose not specified)
[]²⁶	Endophthalmitis		3 months	Prednisolone 40 mg/day

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