03 June 2026
: Case report 
High-Dose Furmonertinib Management of Advanced NSCLC Harboring an EGFR Exon 14 Missense Mutation: A Case Report and Literature Review
Unusual or unexpected effect of treatment, Rare disease
Jing-Yao Luo BEF 1, Jie Xiang BF 2, Xian-liang Hong BF 1, Zhengrong Wang A 2*DOI: 10.12659/AJCR.949630
Am J Case Rep 2026; 27:e949630
Table 1 Multi-gene detection of lung cancer in 2022.
| Lung cancer polygenic detection | ||
|---|---|---|
| Method | PCR (ARMS) | |
| Specimen | Cytological specimen | |
| Item | EGFR | L858 (+) |
| KRAS | (−) | |
| BRAF | (−) | |
| ALK | (−) | |
| ROS1 | (−) | |
| Others | RET, PIK3CA, Her-2, C-MET (14EXON Jump mutation) | All (−) |