03 June 2026
: Case report 
High-Dose Furmonertinib Management of Advanced NSCLC Harboring an EGFR Exon 14 Missense Mutation: A Case Report and Literature Review
Unusual or unexpected effect of treatment, Rare disease
Jing-Yao Luo BEF 1, Jie Xiang BF 2, Xian-liang Hong BF 1, Zhengrong Wang A 2*DOI: 10.12659/AJCR.949630
Am J Case Rep 2026; 27:e949630
Table 2 Baseline Information (2023-11-23).
| Characteristic | Status |
|---|---|
| Age, years | 58 years old |
| ECOG, PS | 0 |
| PD-L1 expressions | Unclear |
| TNM stage | IV |
| Maximum tumor diameter, cm | 2.8 |
| Local invasion | Left upper lung |
| Histological type | Adenocarcinoma |
| Nodal involvement | Left hilar lymph node, mediastinum |
| Sites of metastases | Meninges, bones |
| Ethnicity | Han |
| Education | Junior high school |
| Occupation | Housewife |
| Previous disease history | No previous health problems |
| Tobacco smoking | No |
| Family history | No |
| Marital status | Married |
| Previous therapy | No |
| Finished treatment | |
| Radiotherapy | Head |
| Chemotherapy | Bve+AP 1 cycle |
| Immunotherapy | No |
| Targeted therapy | Icotinib, furmonertinib |
| Follow-up | 8 mouths |