09 December 2025
: Case report 
Behçet Disease and Cognitive Impairment: A Case Study of an Overlooked Symptom
Unknown etiology, Unusual clinical course, Challenging differential diagnosis, Unusual setting of medical care, Rare disease, Clinical situation which can not be reproduced for ethical reasons, Rare coexistence of disease or pathology
Caroline Evanthe Nathania
ABCDEF 1, Astuti Prodjohardjono ACDEF 2,3, Noor Alia Susianti ABCDEF 2*, Abdul Gofir DEF 2,3, Cempaka Thursina Srie Setyaningrum DEF 2,3, Kamala Kan Nur Azza EF 4,5, Ahmad Asmedi F 2,3, Sri Sutarni F 2,3
DOI: 10.12659/AJCR.949699
Am J Case Rep 2025; 26:e949699
Table 3 Qualitative and quantitative measurement of the patient’s brain volumetric.
| No. | Parameter | Volume (cc) |
|---|---|---|
| 1 | Global cortical atrophy (GCA score) | 1 |
| 2 | Temporal lobe atrophy (MTA score) | 1 |
| 3 | Parietal atrophy (Koedam score) | 2 |
| 4 | White Matter hyperintensity (leucoaraiosis) Fazekas classification | 1 |
| 1 | Whole brain | 1061 |
| 2 | Total Intracranial Volume | 1312 |
| 3 | Ratio Whole brain to Total Intracranial Volume | 80% |
| 4 | Right hippocampus | 4.09 |
| 5 | Left hippocampus | 4.04 |
| 6 | Total hippocampus | 8.13 |
| 7 | Total Lateral ventricle | 16.83 |
| 8 | Right cerebellum white matter | 14.54 |
| 9 | Left cerebellum white matter | 14.86 |
| 10 | Right cerebellum cortex | 46.11 |
| 11 | Left cerebellum cortex | 46.01 |
| 12 | Brainstem | 18.83 |
| 13 | Left cerebral cortex | 270.48 |
| 14 | Right cerebral cortex | 268.51 |
| 15 | Total cerebral cortex | 538.99 |
| 16 | Left cerebral white matter | 196.08 |
| 17 | Right cerebral white matter | 196.17 |
| 18 | Total cerebral white matter | 392.25 |
| 19 | Total grey matter | 640.23 |