07 November 2025
: Case report 
Irritation Fibroma on the Tongue Tip Associated With Mandibular Incisors Diastema in a 53-Year-Old Woman: A Case Report
Mistake in diagnosis, Diagnostic / therapeutic accidents, Rare coexistence of disease or pathology
Alaa W. Alqutub
ABEF 1*, Abrar B. Alzahrani ABF 2, Sali A. Sayed ABF 2, Shumukh Y. Balhmer ABF 2, Wareef O. Ghazzawi ABF 2, Abrar K. Demyati ABEF 1
DOI: 10.12659/AJCR.949736
Am J Case Rep 2025; 26:e949736
Table 1 Clinical data of studies reporting irritation fibroma in the oral cavity.
| Author | Location | Cause | Management |
|---|---|---|---|
| Dhanai et al []27 | Maxillary mucosa | Inflammation | Surgical excision |
| Srivastava et al []28 | Palate | Betel chewing and low-grade trauma | Surgical excision |
| Asundaria et al []19 | Lateral border of the tongue | Trauma by sharp cusps | Laser excision |
| Diwan et al []29 | Maxillary mucosa, buccal mucosa | Calculus deposits, traumatic occlusion, and traumatic biting due to orthodontics | Laser excision |
| Lapitskayab et al []30 | Palate | N/A | Surgical excision |
| Cohen []31 | Lower labial mucosa | Self-biting | Surgical excision |
| Tsikopoulos et al []5 | Palate | Trauma from dentures | Surgical excision |
| Ware et al []20 | Maxillary mucosa | Trauma | Surgical excision |
| Salaria et al []32 | Mandibular mucosa | N/A | Surgical excision |
| Lalchandani et al []24 | Maxillary mucosa | Deep bite | Surgical excision |
| Padmanabhan et al []14 | Lateral border of the tongue | N/A | Laser excision |
| Park et al []33 | Mandibular mucosa | N/A | Surgical excision |
| Mahawar et al []34 | Maxillary mucosa | Trauma from dentures | Surgical excision |
| Nascimento et al []35 | Palate | Self-biting | Surgical excision |
| Silva-Mancera et al []22 | Buccal mucosa | Self-biting | Laser excision |
| Jiang et al []7 | Tip of the tongue | N/A | Surgical excision |
| Patait et al []36 | Buccal mucosa | Self-biting, sharp tooth, and trauma from dentures | Laser excision |
| Yadav et al []37 | Mandibular mucosa | Trauma | Surgical excision |
| Jain et al []38 | Mandibular mucosa | N/A | Surgical excision |
| Pinali et al []39 | Maxillary mucosa | N/A | Surgical excision |
| Prasanna et al []40 | Buccal mucosa | Trauma from dentures | Surgical excision |
| Saharan et al []41 | Maxillary mucosa | N/A | Surgical excision |
| Kohli et al []21 | Lower labial mucosa | N/A | Laser excision |
| Jeong et al []42 | Upper labial mucosa | N/A | Surgical excision |
| Practice et al []1 | Buccal mucosa | Self-biting | Laser excision |
| Sabino et al []43 | Buccal mucosa | Self-biting | Surgical excision |
| Bakhtiari et al []6 | Lingual surface of retromolar pad | N/A | Combination of surgical and laser excision |
| Zhao et al []44 | Dorsal surface of the tongue | N/A | N/A |
| Jain et al []45 | Lower labial mucosa | N/A | Surgical excision |
| Rathva et al []3 | Tip of the tongue | Trauma from lower attrided anterior | Surgical excision |