COVID-19-Associated MDA5-Mediated Necrotizing Myositis

17 December 2025 : Case report USA

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease

Sarah Steadman^{ABCDEF 1}, Amit Sikder^{ABCDEF 2}, Harsh R. Desai

^{ABCDEF 3*}, Bradley Collins

^{BE 4}, Tiffany Baker^{BDE 5}, Julie Worthington^{ABCDEF 6}

DOI: 10.12659/AJCR.949788

Am J Case Rep 2025; 26:e949788

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Table 2 Test results for viral infections during hospital admission.

Test	Result	Reference
SARS-CoV-2 Isothermal (NAT)		Negative
Influenza A	Negative	Negative
Influenza B	Negative	Negative
Epstein-Barr virus Capsid antigen IgM antibody	<36.0 U/mL	0.0–35.9
HIV 1 & 2 antibody/P24 antigen	Non-reactive	Non-reactive
Hepatitis A IgM antibody	Negative	Negative
Hepatitis B surface antigen	Negative	Negative
Hepatitis B core IgM antibody	Negative	Negative
Hepatitis C antibody	Non-reactive	Non-reactive

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