Pregnancy and Lactation-Associated Osteoporotic Spinal Fractures: A Case Report

05 November 2025 : Case report China

Mistake in diagnosis, Diagnostic / therapeutic accidents, Rare disease, Clinical situation which can not be reproduced for ethical reasons

Wenhua Lan^{BCDEF 1}, Zhiliang Guo^{BCD 2}, Yongtian Jiang^{BCF 2}, Haijiang Lu^{BCD 2}, Dahai Zhang^{BCD 2}, Wennan Du^{ABCDEF 3*}

DOI: 10.12659/AJCR.949815

Am J Case Rep 2025; 26:e949815

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Table 1 Bone mineral density (BMD) before and after 19 months of treatment.

Examination site	Examination area	Pre-treatment BMD (g/cm2)	T-Score	Z-Score	Post-treatment BMD (g/cm2)	T-Score	Z-Score
Hip	Neck	0.617	−2.1	−2.0	0.631	−2.0	−1.8
	Trochanter	0.491	−2.1	−2.1	0.481	−2.2	−2.2
	Interior	0.741	−2.3	−2.3	0.706	−2.5	−2.5
	Total	0.657	−2.3	−2.3	0.628	−2.6	−2.5
	Ward’s	0.347	−3.3	−3.1	0.368	−3.1	−2.8
Lumbar	L1	0.607	−3.5	−3.5	0.655	−3.0	−3.0
	L2	0.658	−3.4	−3.3	0.681	−3.2	−3.1
	L3	0.683	−3.6	−3.6	0.719	−3.3	−3.3
	L4	0.700	−3.3	−3.3	0.723	−3.1	−3.0
	Total	0.666	−3.5	−3.4	0.698	−3.2	−3.1
The BMD examination conducted after 19 months of treatment showed slight improvement in lumbar spine BMD; hip BMD demonstrated no clinically significant improvement and, in some regions, a decrease.

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