Bacteremia and Liver Failure Due to Non-K1 Escherichia coli With iss Gene in Two Full-Term Infants

23 April 2026 : Case report Japan

Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Rare coexistence of disease or pathology

Yuuki Shikaze^{ABCDEF 1}, Shinsuke Mizuno

^{ABCDEF 1*}, Ryousuke Bou^{BCDF 2}, Hiroshi Kurosawa

^{BCDF 3}, Naoko Imuta^{CDF 4}, Junichiro Nishi^{CDF 4}, Masashi Kasai^{ABDF 1}

DOI: 10.12659/AJCR.949819

Am J Case Rep 2026; 27:e949819

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Table 1 Laboratory findings in cases 1 and 2 during hospitalization.

	Day 1	Day 2	Day 3	Day 4	Day 5	Day 6	Day 7	Day 8	Day 9	Day 10

WBC count (10/L)	4.4	11.6	15.4	11.7	10.3	12.1	11.1	12.2	15.2	11.3
CRP (mg/dL)	3.6	4.6	4.2	1.5	1.4	0.3	0.3	0.4	0.5	0.6
PLT count (10/L)	150	44	27	19	92	18	14	38	116	35
PT (%)	68	52	47	68	39	36	30	30	40	39
ALB (mg/dL)	4.9	4.4	4.2	3.3	3.9	4.1	4.4	4.7	4.9	4.8
AST (U/L)	38	21	37	34	21	21	23	30	36	41
ALT (U/L)	29	17	37	28	16	13	11	13	17	17
T-Bil (mg/dL)	7.9	9.0	13.1	11.0	6.7	6.0	6.8	7.7	8.9	9.2
D-Bil (mg/dL)		4.3	5.7	5.1	3.3	3.2	3.7	3.8	4.8	5.2
NH (mg/dL)	77	51	62	63	51	53	65	64	104	48

WBC count (10/L)	8.6	4.7	5.9	5.3	5.3	3.7	4.8	6.5
CRP (mg/dL)	<0.1	<0.1	<0.1	<0.1	<0.1	<0.1	<0.1	0.1
PLT count (10/L)	36	47	31	109	52	93	67	142
PT (%)	22	54	44	54	46	70	72	57
ALB (mg/dL)	2.0	2.9	3.4	3.5	3.0	3.8	3.9	3.7
AST (U/L)	23	36	20	27	17	24	24	22
ALT (U/L)	21	17	21	21	15	19	20	12
T-Bil (mg/dL)	7.3	9.8	11.7	12.4	9.8	13.1	14.2	9.8
D-Bil (mg/dL)			1.1	1.1		1.0	1.3	0.9
NH (mg/dL)	73	80	75	141	148	115	85	81
ALB – albumin; ALT – alanine aminotransferase; AST – aspartate aminotransferase; CRP – C-reactive protein; D-Bil – direct bilirubin; PLT – platelets; PT – prothrombin time; T-Bil – total bilirubin; WBC – white blood cell.

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