23 October 2025
: Case report 
Left Ventricle Libman-Sacks Endocarditis Secondary to Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report
Unusual clinical course, Rare disease
Zi-hao Yang BCEF 1, Wen-qing Gong BDFG 1, Ying Liu ABF 2, Min-juan Zheng ACG 1*DOI: 10.12659/AJCR.949826
Am J Case Rep 2025; 26:e949826
Table 1 Laboratory parameters at admission, pre-discharge, and 6-month follow-up.
| Parameter | Admission | Pre-discharge | 6-month follow-up | Normal range |
|---|---|---|---|---|
| Autoantibodies | ||||
| ANA | 1: 10 000 | 1: 400 | 1: 200 | <1: 80 |
| Anti-dsDNA antibody (IU/mL) | 49 | 10 | 9 | 0~10 |
| Anti-Sm antibody (AU/mL) | 15 | <1.0 | <1.0 | <1.0 |
| ACA (IgG) (IU/mL) | 193 | 21 | 5 | <12 |
| Anti-β2GPI antibody (RU/mL) | 300 | 44 | 10 | <20 |
| Anti-Ro-52 antibody (RU/mL) | 96 | 19 | 8 | <10 |
| Complement | ||||
| C3 (mg/dL) | 42.1 | 85 | 120 | 90–180 |
| C4 (mg/dL) | 3 | 11 | 35 | 10–40 |
| Inflammation, hematology, cardiac | ||||
| ESR (mm/h) | 96 | 18 | 12 | <20 |
| Platelet count (×10/L) | 89 | 90 | 118 | 100–300 |
| Hemoglobin (g/L) | 66 | 72 | 112 | 110–150 |
| NT-ProBNP (ng/L) | 126.1 | 120.0 | 72.4 | <125 |
| ANA – antinuclear antibody; Anti-dsDNA antibody – anti-double-stranded DNA antibody; Anti-β2GPI – anti-β2-glycoprotein I antibody; ACA – Anti-cardiolipin antibody; C3 – complement 3; C4 – complement 4; ESR – erythrocyte sedimentation rate; NT-proBNP – N-terminal pro-B-type natriuretic peptide. | ||||