25 December 2025
: Case report 
Guillain-Barré Syndrome in the Third Trimester of Pregnancy: A Case Report and Literature Review
Rare disease
Liang Gao ABCDEF 1, Mouchang Qiu BF 1, Hua Qian ADE 1*DOI: 10.12659/AJCR.949852
Am J Case Rep 2025; 26:e949852
Table 1 Summary of reported cases of Guillain-Barré syndrome (GBS) during pregnancy and postpartum.
| Author | Patient age (years) | Preceding events | Treatment | Delivery timing (weeks) & mode | Maternal outcome | Fetal outcome (Apgar score) |
|---|---|---|---|---|---|---|
| Wang et al []25 | 34 | Upper respiratory infection | IVIG | 34, CS | Recovered | 9–9 |
| Swonger et al []26 | 38 | Vaccination | IVIG | 38+6, CS | Recovered | 9–9 |
| Okahara et al []27 | 30 | Upper respiratory infection, vaccination | IVIG | 34+1, CS | Recovered | 9–9 |
| Iliadi-Tulbure et al []11 | 34 | Upper respiratory infection | PLEX & IVIG | 33, CS | Recovered | 7–8 |
| Maqbool et al []28 | 25 | Upper respiratory infection | GCs & PLEX | Postpartum | Recovered | Not reported |
| Arun et al []29 | 28 | Campylobacter/COVID-19 | IVIG | 36, CS | Nearly recovered | Not reported |
| Corder et al []30 | 24 | Unknown | PLEX & IVIG | 39+2, vaginal delivery after induction | Recovered | 9–9 |
| IVIG – intravenous immunoglobulin; PLEX – plasma exchange; GCs – glucocorticoids; CS – cesarean section. Apgar score at 1 and 5 minutes after birth is shown as “x–y”. Not reported indicates data not available in the original report. | ||||||