15 January 2026
: Case report 
Anaphylaxis and Cardiac Arrest Induced by Initial Intravenous Ceftriaxone: A Case Report
Management of emergency care, Unexpected drug reaction, Rare disease
Zhichu Dai ABCDEF 1, Jiankun Liao ABCDE 2, Liwei He ABFG 1*DOI: 10.12659/AJCR.949917
Am J Case Rep 2026; 27:e949917
Table 1 Naranjo adverse drug reaction probability scale.
| Question | Yes | No | Do not know | Score |
|---|---|---|---|---|
| 1. Are there previous conclusive reports on this reaction? | +1 | 0 | 0 | 1 |
| 2. Did the adverse event appear after the suspected drug was administered? | +2 | −1 | 0 | 2 |
| 3. Did the adverse reaction improve when the drug was discontinued or a specific antagonist was administered? | +1 | 0 | 0 | 1 |
| 4. Did the adverse event reappear when the drug was re-administered? | +2 | −1 | 0 | 0 |
| 5. Are there alternative causes (other than the drug) that could on their own have caused the reaction? | −1 | +2 | 0 | 2 |
| 6. Did the reaction reappear when a placebo was given? | −1 | +1 | 0 | 0 |
| 7. Was the drug detected in blood (or other fluids) in concentrations known to be toxic? | +1 | 0 | 0 | 0 |
| 8. Was the reaction more severe when the dose was increased or less severe when the dose was decreased? | +1 | 0 | 0 | 0 |
| 9. Did the patient have a similar reaction to the same or similar drugs in any previous exposure? | +1 | 0 | 0 | 0 |
| 10. Was the adverse event confirmed by any objective evidence? | +1 | 0 | 0 | 1 |