Thrombolytic Therapy After Return of Spontaneous Circulation in Patients With STEMI From Medically Underdeveloped Areas: A Case Series

Jiacheng Lai; Chongjian Huang; Lei Wang; Renli Cheng; Qingtong Wang; Yongsheng Han

doi:10.12659/AJCR.949976

27 January 2026 : Case report China

Thrombolytic Therapy After Return of Spontaneous Circulation in Patients With STEMI From Medically Underdeveloped Areas: A Case Series

Management of emergency care

Jiacheng Lai^{ABCE 1,2}, Chongjian Huang

^{AB 2,3}, Lei Wang^{B 4}, Renli Cheng^{B 3}, Qingtong Wang^{FG 5}, Yongsheng Han^{AFG 2,6*}

DOI: 10.12659/AJCR.949976

Am J Case Rep 2026; 27:e949976

Authors information Article notes Copyright and License information

Introduction Case Reports Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Table 2 Patients’ clinical characteristics and treatment outcomes.

Patient number	Age	Sex	History of hyper-tension	History of diabetes	History of coronary heart disease	History of cerebral infarction	Smoker	Basic anti-platelet rherapy	Location of onset	ECG site	Delayed treatment (min)	CPR duration (min)
1	52	M	No	No	No	No	Yes	/	Out of hospital	Anterior wall	5	40
2	64	M	No	No	Yes	Yes	No	Aspirin	In hospital	Inferior wall	0	20
3	67	F	No	No	No	Yes	No	Aspirin	Out of hospital	Extensive anterior wall	15	30
4	36	M	No	No	No	No	Yes	/	Out of hospital	Extensive anterior wall	5	10
5	68	M	No	No	Yes	No	Yes	Aspirin	In hospital	Inferior wall	0	14
6	62	M	No	No	No	No	No	/	In hospital	Anterior wall	0	15
7	82	F	No	No	No	No	No	/	Out of hospital	Inferior wall	5	10
8	74	M	Yes	No	No	Yes	Yes	Aspirin	Out of hospital	Extensive anterior wall	6	5
9	72	F	Yes	No	No	No	No	/	In hospital	Inferior wall	0	40
10	51	M	Yes	No	No	No	Yes	/	In hospital	Extensive anterior wall	0	30
11	62	M	No	No	No	No	Yes	/	In hospital	Extensive anterior wall	0	6
12	82	M	Yes	Yes	Yes	No	No	Aspirin	Out of hospital	Extensive anterior wall	5	23
BARC – Bleeding Academic Research Consortium; CPC – cerebral performance category; CPR – cardiopulmonary resuscitation; ECG – electrocardiography; F – Female; ICU – intensive care unit; M – Male; PCI – percutaneous coronary intervention; rhPro-UK – recombinant human prourokinase.
Patient number	Antiplatelet therapy	Drug type	Thrombolysis result	BARC type	Rib fractures	Hospitalization Length (days)		CPC Score	PCI	Prognosis		Sequela	Cause of death
Patient number	Antiplatelet therapy	Drug type	Thrombolysis result	BARC type	Rib fractures	ICU	General Ward	CPC Score	PCI	30-Day	1-Year	Sequela	Cause of death
1	Aspirin + clopidogrel	Urokinase	Successful	Type 2	Yes	3	8	1	No	Survival	Survival	Unresponsive	/
2	Aspirin + clopidogrel	Urokinase	Successful	Type 2	Yes	13	8	1	No	Survival	Death	Right limb muscle strength grade IV	Recurrent cardiac arrest
3	Aspirin + clopidogrel	Urokinase	Successful	Type 5	Yes	13	0	4	No	Death	/	Died	Digestive tract hemorrhage
4	Aspirin + clopidogrel	rhPro-UK	Successful	Type 0	No	3	14	1	Yes	Survival	Survival	/	/
5	Aspirin + clopidogrel	rhPro-UK	Successful	Type 0	No	4	9	1	No	Survival	Survival	/	/
6	Aspirin + clopidogrel	rhPro-UK	Successful	Type 1	No	4	9	1	Yes	Survival	Survival	/	/
7	Aspirin + clopidogrel	rhPro-UK	Failed	Type 0	No	0	0	5	No	Death	/	Died	Unsuccessful thrombolytic therapy
8	Aspirin + clopidogrel	rhPro-UK	Successful	Type 2	Yes	10	0	4	No	Death	/	Died	Severe cerebral dysfunction
9	Aspirin + ticagrelor	rhPro-UK	Successful	Type 0	Yes	7	6	1	Yes	Survival	Survival	/	/
10	Aspirin + ticagrelor	rhPro-UK	Successful	Type 0	Yes	4	13	1	Yes	Survival	Survival	/	/
11	Aspirin + ticagrelor	rhPro-UK	Successful	Type 0	No	0	14	1	Yes	Survival	Survival	/	/
12	Aspirin + ticagrelor	rhPro-UK	Successful	Type 2	Yes	0	9	1	Yes	Survival	Survival	/	/
BARC – Bleeding Academic Research Consortium; CPC – cerebral performance category; CPR – cardiopulmonary resuscitation; ECG – electrocardiography; F – Female; ICU – intensive care unit; M – Male; PCI – percutaneous coronary intervention; rhPro-UK – recombinant human prourokinase.

Back to the Article

Thrombolytic Therapy After Return of Spontaneous Circulation in Patients With STEMI From Medically Underdeveloped Areas: A Case Series

Your Privacy