Histiocytic Sarcoma Treated With Autologous Stem Cell Transplantation: A Case Report and Literature Review of the Role of Autologous and Allogenic Stem Cell Transplantation

25 January 2026 : Case report South Korea

Rare disease

Yun Ji Lee

^{BCDEF 1}, Dong Won Baek

^{AF 1*}

DOI: 10.12659/AJCR.950225

Am J Case Rep 2026; 27:e950225

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Table 1 Treatment schedule of the patients with CHOEP, BuCyE, and ICE regimen.

Regimen	Drug	Dose	D1	D2	D3	D4	D5	D6	D7
CHOEP	Cyclophosphamide	750 mg/m	O
	Doxorubicin	50 mg/m	O
	Vincristine	2 mg	O
	Etoposide	100 mg/m	O
	Prednisolone	100mg	O	O	O	O	O
BuCyE	Busulfan	3.2 mg/m	O	O	O
	Etoposide	350 mg/m				O	O
	Cyclophosphamide	50 mg/m						O	O
	Ifosfamide	5 g/m		O
ICE	Mesna	Equal dose to ifosfamide divided pre (1000 mg/m) during (4000 mg/m)		O
	Etoposide	100 mg/m	O	O	O
	Carboplatin	AUC 5		O
All regimens were repeated every 21 days, except for BuCyE, which was used as a conditioning regimen prior to transplantation. CHOEP – cyclophosphamide-doxorubicin-vincristine-etoposide-prednisone; BuCyE – busulfan-cyclophosphamide-etoposide; ICE – ifosfamide-carboplatin-etoposide.

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