07 February 2026
: Case report 
Coronary Artery Bypass Grafting in the Presence of Severe Hyperthyroidism: A Case Report
Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Unexpected drug reaction, Educational Purpose (only if useful for a systematic review or synthesis)
Akie Shimada BE 1, Taira Yamamoto ACEF 1*, Jiyoung Lee B 1, Shizuyuki Dohi D 1, Daisuke Endo
D 2, Yuichiro Sato C 2, Yasutaka Yokoyama C 2, Minoru Tabata A 2
DOI: 10.12659/AJCR.950442
Am J Case Rep 2026; 27:e950442
Table 1 Changes in laboratory test results after hospitalization.
| Test | Reference range | Day 0 (at admission) | Day 7 (after admission) | Day 14 (after admission) | Day 21 (after admission) |
|---|---|---|---|---|---|
| Blood pressure (mmHg) | 156/94 | 122/70 | 112/68 | 110/60 | |
| Heart rate (bpm) | 110 | 76 | 78 | 64 | |
| Body temperature (°C) | 37.0 | 38.0 | 36.9 | 36.6 | |
| TSH (mIU/L) | 4.23-0.61 | <0.005 | <0.005 | <0.005 | 0.006 |
| FT3 (pg/mL) | 4.50-2.40 | 16.14 | 12.30 | 8.88 | 7.75 |
| FT4 (ng/dL) | 1.70-1.00 | 7.57 | 6.45 | 4.15 | 3.35 |
| TRAb 3 (IU/L) | 1.30-0.00 | 4.18 | |||
| Anti TPOAb (IU/L) | 3.3-0.0 | 25.5 | |||
| Anti TGAb (IU/mL) | 19.3-0.0 | 96.7 | |||
| Thyroglobulin (ng/mL) | 35.1-0.0 | 66.0 | |||
| N-terminal pro-brain Natriuretic peptide (pg/mL) | 125.00-0.00 | 477.90 | 274.00 | 192.50 | 156.70 |
| White blood cells (×10/L) | 9.7-3.9 | 5.5 | 4.4 | 2.6 | 3.9 |
| C-reactive protein (mg/dL) | 0.29-0.00 | 0.96 | 0.21 | 0.13 | 0.04 |
| Hemoglobin (g/dL) | 17.1-13.4 | 12.6 | 12.9 | 13.0 | 12.9 |
| Platelet (×10/μL) | 34.6-15.3 | 13.3 | 16.4 | 11.7 | 10.6 |
| PT-INR | 1.15-0.85 | 1.01 | 1.01 | 1.01 | 0.99 |
| aPTT (s) | 40.7-24.4 | 28.6 | 27.2 | 29.6 | 21.9 |
| AST (U/L) | 37-5 | 20 | 26 | 24 | 27 |
| ALT (U/L) | 43-6 | 19 | 40 | 30 | 35 |
| Total bilirubin (mg/dL) | 1.2-0.4 | 0.6 | 0.7 | 0.5 | 0.5 |
| Direct bilirubin (mg/dL) | 0.3-0.1 | 0.2 | |||
| Total protein (g/dL) | 8.5-6.5 | 6.1 | |||
| Albumin (g/dL) | 5.2-3.8 | 3.4 | 3.7 | 3.5 | 4.0 |
| Total cholesterol (mg/dL) | 219-150 | 103 | |||
| Triglyceride (mg/dL) | 149-30 | 116 | |||
| High-density lipoprotein cholesterol (mg/dL) | 70-40 | 30 | |||
| Low-density lipoprotein cholesterol (mg/dL) | 139-70 | 56 | |||
| Hemoglobin A1c (%) | 6.2-4.6 | 6.8 | |||
| TSH – thyroid stimulating hormone; FT3 – serum thyroid hormone-free triiodothyronine; FT4 – serum thyroid hormone-free thyroxine; TRAb 3 – thyroid stimulating hormone receptor antibody titers measured with a third-generation assay; Anti-TPOAb – anti-thyroid peroxidase antibody; Anti TGAb – anti-thyroid-globulin antibody; PT-INR – prothrombin time-international normalized ratio; aPTT – activated partial thromboplastin time; AST – aspartate aminotransferase; ALT – alanine aminotransferase. | |||||