07 January 2026
: Case report 
Endoscopic-Assisted Excision of Parotid Castleman Disease in Pediatric Patients: A Case Series of Three Patients and a Literature Review
Unusual or unexpected effect of treatment, Rare disease
Wenli Wu
AE 1*, Ping Xu D 2, Jiawei Lin B 1, Wenqin Lian C 1, Fan Li F 1
DOI: 10.12659/AJCR.950918
Am J Case Rep 2026; 27:e950918
Table 1 Summary of published cases of parotid Castleman disease in pediatric patients.
| Case No. | Year | Country | Author [Ref] | Sex | Age (years) | Site | U/M centric | Maximum diameter (cm) |
|---|---|---|---|---|---|---|---|---|
| 1 | 2003 | USA | Samadi et al []2 | M | 12 | Left parotid | U | 4.5 |
| 2 | 2004 | India | Mohan et al []8 | M | 17 | Right parotid | U | 4.5 |
| 3 | 2006 | Peru | Mohanna et al []14 | F | 6 | Left parotid | U | 3.5 |
| 4 | 2008 | Turkey | Erdogan et al []9 | F | 15 | Left parotid | U | 4.8 |
| 5 | 2008 | Italy | Caselli et al []10 | M | 16 | Right parotid | U | 4.3 |
| 6 | 2008 | Korea | Park et al []5 | M | 9 | Left parotid | U | 3.0 |
| 7 | 2010 | China | Zhong et al []11 | F | 13 | Right parotid and neck | U | 4.0 |
| 8 | 2014 | Oman | Kumar et al []12 | M | 15 | Right parotid | U | 2.5 |
| 9 | 2014 | Turkey | Varsak et al []6 | M | 12 | Left parotid | U | 3.5 |
| 10 | 2014 | USA | Bollig et al []15 | M | 14 | Right parotid | U | 3.3 |
| 11 | 2015 | USA | Delaney et al []7 | F | 11 | Right parotid | U | 3.5 |
| 12 | M | 7 | Right parotid | U | 3.6 | |||
| 13 | 2021 | Iran | Kardouni Khoozestani et al []13 | M | 15 | Left parotid | U | 3.0 |
| 1 | 6 years | N | Asymptomatic | Complete excision | HV | 12 months, alive and disease-free | ||
| 2 | 2 years | N | Asymptomatic | Superficial parotidectomy | HV | Not mentioned | ||
| 3 | 18 months | N | Local pain | Complete excision | HV | 10 years, alive and disease-free | ||
| 4 | Not mentioned | N | Asymptomatic | Complete excision | HV | Not mentioned | ||
| 5 | 1 year | N | Weakness and mild fever | Parotidectomy | HV | 24 months, alive and disease-free | ||
| 6 | 3 months | N | Asymptomatic | Superficial parotidectomy | HV | 24 months, alive and disease-free | ||
| 7 | 48 months | N | Asymptomatic | Complete excision | HV | 33 months, alive and disease-free | ||
| 8 | 3 months | N | Asymptomatic | Superficial parotidectomy | HV | 4 years, alive and disease-free | ||
| 9 | 4 years | N | Asymptomatic | Total mass excision | HV | 12 months, alive and disease-free | ||
| 10 | 1 year | N | Asymptomatic | Superficial parotidectomy | HV | Lost to follow-up | ||
| 11 | 3 years | N | Asymptomatic | Superficial parotidectomy | HV | 6 months, alive and disease-free | ||
| 12 | 1 year | N | Asymptomatic | Superficial parotidectomy | HV | 12 months, alive and disease-free | ||
| 13 | 4 years | N | Asymptomatic | Superficial parotidectomy | HV | Fever, night sweats, abdominal masses | ||
| F – Female; M – Male; U – unicentric; HV – hyaline vascular type; USA – United States of America. | ||||||||