29 December 2025
: Case report 
Growth Hormone Response in a Child With a Homozygous TOMM7 Mutation: Novel Therapeutic Insights
Unusual setting of medical care, Rare disease
Shu Liu BC 1, Wei Lu DF 2, Lin Yang DF 2, Xiubin Tong BE 1, Xiu Xu A 3, Huiping Li AEFG 3*DOI: 10.12659/AJCR.950967
Am J Case Rep 2025; 26:e950967
Table 1 Anthropometric measurements of the child from birth to 39 months of age.
| Age (months) | Height (cm), SDS | Weight (kg), SDS | Head circumference (cm), SDS | Notes |
|---|---|---|---|---|
| Birth | 50.0, 0.06 | 3.2, −0.30 | – | – |
| 1 month | 55.5, 0.40 | 5.2, 1.15 | – | – |
| 3.5 months | 64.0, 0.65 | 7.0, 0.40 | – | – |
| 6 months | 67.0, −0.29 | 8.0, 0.08 | – | – |
| 10 months | 68.0, −2.31 | 8.1, −1.13 | 45.0, −0.32 | – |
| 14 months | 72.3, −2.32 | 9.0, −1.04 | 46.0, −0.45 | – |
| 18 months | 74.8, −2.77 | 8.7, −2.05 | – | – |
| 21 months | 76.8, −2.90 | 9.4, −1.83 | – | – |
| 24 months | 78.1, −3.18 | 9.5, −2.16 | – | – |
| 27 months | 78.0, −3.26 | 9.5, −3.09 | – | – |
| 31 months | 78.2, −4.05 | 9.3, −3.78 | 47.2, −1.36 | Fasting |
| 33 months | 78.8, −4.30 | 9.1, −4.27 | – | Fasting |
| 34 months | 78.6, −4.58 | 10.0, −3.36 | 48.4, −0.72 | Non-fasting |
| 36 months | 79.3, −4.58 | 9.6, −4.06 | 49.0, −0.42 | Fasting |
| 38 months | 80.2, −4.57 | 10.3, −3.51 | – | Non-fasting |
| 39 months | 81.1, −4.39 | 10.4, −3.52 | 48.7, – | Fasting |
| SDS – standard deviation score. 1. All measurements were taken using standard anthropometric techniques; 2. “–“ indicates data not available or not measured; 3. Fasting or non-fasting status is noted when specified in the original records; 4. Growth parameters were assessed using the United States Centers for Disease Control and Prevention growth charts. | ||||