29 December 2025
: Case report 
Growth Hormone Response in a Child With a Homozygous TOMM7 Mutation: Novel Therapeutic Insights
Unusual setting of medical care, Rare disease
Shu Liu BC 1, Wei Lu DF 2, Lin Yang DF 2, Xiubin Tong BE 1, Xiu Xu A 3, Huiping Li AEFG 3*DOI: 10.12659/AJCR.950967
Am J Case Rep 2025; 26:e950967
Table 2 Longitudinal laboratory parameters from 9 to 39 months of age.
| Parameter | Unit | 9 mo | 31 mo | 33 mo | 36 mo | 39 mo |
|---|---|---|---|---|---|---|
| CK | U/L | 233 | – | 109.3 | 91.2 | 108 |
| CK-MB | U/L | 32.4 | – | 42.2 | 25.4 | 26.9 |
| LDH | U/L | 337 | – | 306.6 | 251.3 | 254.9 |
| Glucose | mmol/L | 5.31 | – | 3.19 | – | 4.32 |
| IGF-1 | ng/mL | – | 76.4 | 72.9 | 161 | 333 |
| IGF-BP3 | ng/mL | – | – | – | 4126 | 4843 |
| CK – creatine kinase; CK-MB – creatine kinase-MB; LDH – lactate dehydrogenase; IGF-1 – insulin-like growth factor 1; IGF-BP3 – insulin-like growth factor binding protein 3; mo – months. 1. Data are presented as measured values; “–“ indicates unavailable data; 2. All measurements were performed using standard clinical laboratory protocols. | ||||||