Hemoglobin San Diego: A Case Report and Review of the Literature

14 April 2026 : Case report USA

Challenging differential diagnosis, Rare disease

Matthew L. Repp^{ABEF 1*}, Brandon McMahon^{ABEF 1,2}

DOI: 10.12659/AJCR.951364

Am J Case Rep 2026; 27:e951364

Authors information Article notes Copyright and License information

Introduction Case Report Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Table 1 Laboratory test results in the evaluation of primary and secondary causes of erythrocytosis.

	Test	Result	Reference range
CBC	Hemoglobin (g/dL)	18.7	14.3–18.1
	Hematocrit (%)	53.9	39.2–50.2
	Red blood cell count (10/L)	5.81	4.76–6.09
	Mean corpuscular volume (fL)	92.8	80.0–100.0
	White blood cell count (10/L)	5.6	4.0–11.1
	Platelet count (10/L)	96	150–400
Erythrocytosis evaluation	JAK2 V617F mutation analysis (PCR)	Negative	Negative
	JAK2 exon 12 mutation analysis (PCR)	Negative	Negative
	Erythropoietin (mU/mL)	22	4–27
	Testosterone (ng/dL)	490.24	123.06–813.86
	Hemoglobin stability test	Normal	Normal
	Genetic testing	Gene: HBB; legacy nomenclature: β109 GTG>ATG (Val>Met), heterozygous	Normal
CBC – complete blood count; HBB – hemoglobin subunit beta gene; JAK2 – Janus kinase 2; PCR – polymerase chain reaction.

Back to the Article