21 May 2026
: Case report 
A Singleton Male Infant With Aplasia Cutis Congenita Type V Associated With Single Umbilical Artery and Atrial Septal Defect: A Case Report
Challenging differential diagnosis, Unusual setting of medical care, Congenital defects / diseases, Educational Purpose (only if useful for a systematic review or synthesis)
Jesús J. Martínez-García
AE 1,2*, Lourdes Elizabeth Zamudio-García BC 3, Melissa Martínez-Félix BC 4, Uriel A. Angulo-Zamudio DF 2, Hector Flores-Villaseñor DF 2, Erika Acosta-Smith AF 5, Adrian Canizalez-Román DE 2,6, Nidia León-Sicairos CDE 2,7
DOI: 10.12659/AJCR.951885
Am J Case Rep 2026; 27:e951885
Table 1 Comparison of published cases of symmetrical truncal ACC.
| Feature | Current case (2025) | Tekinalp et al (1997) [10] | Suliman et al (2004) [20] | Ahmed et al (2024) [19] |
|---|---|---|---|---|
| 39 weeks | Not reported | Full-term (not specified) | ||
| Bilateral abdomen | Bilateral trunk | Bilateral trunk (triangular lesions linked by narrow band below umbilicus) | ||
| Symmetrical | Symmetrical | Symmetrical, triangular | ||
| Not documented | Not evaluated | Not evaluated | ||
| Not reported | Not performed | Not performed | ||
| ASD (method not specified) | None reported | None (echocardiography normal) | ||
| Not performed | Not performed | Not performed | ||
| Not reported | Not reported | Not performed (clinical diagnosis only) | ||
| Not specified | Not classified | Not classified (authors proposed new subtype) | ||
| Conservative management (details not specified) | Conservative management (details not specified) | Silver sulfadiazine 1% dressing (once daily ×1 week, then every 2 days ×3 weeks) | ||
| Complete healing | Complete healing | Complete healing in ~1 month with mature scar tissue and hypopigmentation | ||
| First report of ACC + ASD association, but incomplete vascular workup | Similar morphology, but no vascular investigation | Most morphologically similar case; absence of SUA evaluation prevented Type V classification | ||
| ACC – aplasia cutis congenita; SUA – single umbilical artery; ASD – atrial septal defect. ✓ indicates completed investigation. | ||||