27 April 2026
: Case report 
Management of Bilateral Humeral Head Avascular Necrosis in Sickle Cell Disease Using Surgical Intervention With Adjuvant Hyperbaric Oxygen Therapy: A Case Report
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction, Clinical situation which can not be reproduced for ethical reasons, Rare coexistence of disease or pathology
Abdulla A. Aljowder ACG 1, Waleed Y. Ebrahim E 1, Omar Abusedera ABDEF 2*, Konouz Alfadhli ABCDEFG 2, Noor Jaragh ACDE 2, Leen Zghaier EF 2, Awrad J. Alkhaldi BEF 2DOI: 10.12659/AJCR.951902
Am J Case Rep 2026; 27:e951902
Table 1 Baseline laboratory findings of the patient.
| Parameter | Patient value | Normal range | Note |
|---|---|---|---|
| Hb | 8.6 g/dL | 13.5–17.5 g/dL (male) 12–16 g/dL (female) | Low, consistent with chronic SCD anemia |
| Hct | 26% | 41–53% (male) 36–46% (female) | Low |
| Reticulocyte count | 6.8% | 0.5–2.5% | Elevated, indicates compensatory erythropoiesis |
| WBC | 9.8×10/L | 4–11×10/L | Within expected range |
| Platelet count | 410×10/L | 150–450×10/L | Within expected range |
| ESR | 18 mm/hr | 0–20 mm/h | Normal |
| CRP | 4 mg/L | <10 mg/L | Normal |
| HbS fraction | 78% | <5% (normal adults) | High, consistent with homozygous SCD |
| Hb – hemoglobin; Hct – hematocrit; Retic – reticulocyte count; WBC – white blood cell count; Plt – platelet count; ESR – erythrocyte sedimentation rate; CRP – C-reactive protein; HbS – hemoglobin S. Normal ranges are provided for reference. | |||