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08 July 2026 : Case report  China

Misdiagnosis of Endometrioid Borderline Ovarian Tumors by Intraoperative Frozen Section Pathology: A Case Report and Review of the Literature

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction, Rare disease, Educational Purpose (only if useful for a systematic review or synthesis)

Huifen Wang AB 1, Hongqin Du A 1*

DOI: 10.12659/AJCR.952134

Am J Case Rep 2026; 27:e952134

Table 1 Immunohistochemical staining results of the bilateral endometrioid borderline ovarian tumor case.

Antibody/markerResultNotes
PAX-8Negative
VimentinNegative
WT-1Negative
p16Negative
p53Negative
ERPositive
PRPositive
MLH1Positive
MSH2Positive
MSH6Positive
PMS2Positive
CA125Positive
Ki-67PositiveApproximately 10–20%
Abbreviations: CA, cancer antigen; ER, estrogen receptor; PR, progesterone receptor; WT-1, Wilms tumor 1; MLH, MutL homolog; p16, tumor protein 16; p53, tumor protein 53; PMS2, postmeiotic segregation increased 2; PAX-8, paired box gene 8.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923