25 June 2026
: Case report
Posterior Reversible Encephalopathy Syndrome Associated With Post-Streptococcal Glomerulonephritis in a Young Adult: A Case Report and Literature Review
Mistake in diagnosis, Unusual or unexpected effect of treatment, Rare coexistence of disease or pathology
Mahmoud H.S. DaoudDOI: 10.12659/AJCR.952209
Am J Case Rep 2026; 27:e952209
Table 2 Summary of reported PRES cases associated with PSGN, including clinical features, imaging findings, management, and outcome.
| Author/year | Age/sex | Neurological manifestations | Renal findings | Blood pressure at presentation | Neuroimaging findings | Management | Outcome |
|---|---|---|---|---|---|---|---|
| Castellano-Martinez A []/2022 first case13 | 11 yo male | Somnolence, seizures, headache, and blurry vision. | Hematuria and acute kidney injury | 160/100 mmHg (95 percentile) | Symmetrical areas of cortico-subcortical hyperintensity in the temporo-occipital and frontoparietal regions of both cerebral hemispheres | Antihypertensive and anticonvulsant | Complete recovery |
| Castellano-Martinez A []/2022 second case13 | 9 yo male | Seizures and headache | Hematuria and acute kidney injury | 170/110 mmHg (95 percentile) | Symmetrical areas of cortico-subcortical hyperintensity in the temporo-occipital and frontoparietal regions of both cerebral hemispheres | Antihypertensive and anticonvulsant | Significant improvement with persistent microscopic hematuria |
| Bazhu []/202214 | 14 yo female | Headache, dizziness, seizures, and vomiting | Hematuria (3 +), proteinuria and azotemia (urea 7.33 mmol/L, serum creatinine 168 μmol/L) | 150/90 | High-intensity signals in the bilateral frontal, parietal, and occipital lobes | Antihypertensive and anticonvulsant | Significant improvement |
| Kharbat AF []/202215 | 8 yo male | Seizures, blurred vision, headache | Hematuria and renal dysfunction | 155–192/114–132 | Subcortical edema of various brain regions, including occipital, temporal, and parietal cortices | Antihypertensive and anticonvulsant drugs | Improved with stable blood pressure |
| Harikrishna GV []/202316 | 15 yo male | Headache, visual disturbances, and involuntary movements of all 4 limbs | Proteinuria and hematuria | 150/100 mmHg (99 percentile as per the Indian Pediatric Association) | Symmetrical enhancement of superficial and deep watershed areas, predominantly in the occipital and temporal regions | Antihypertensive and anticonvulsant | Complete resolution |
| Han Q []/20256 | 22 yo female | Headache, consciousness disturbance, and seizures | Hematuria (3 +), proteinuria (3+) and azotemia (urea 14.2 mmol/L, serum creatinine 187.8 μmol/L) | 132/84 | Multiple edemas in the cortex and subcortical areas of the bilateral cerebral hemispheres | Antihypertensive and anticonvulsant | Complete recovery |
| Presented case | 20 yo male | Headache, loss of vision and seizures | 3+ proteinuria, granular casts, microscopic hematuria, red blood cell casts and acute kidney injury | 147/86 | Bilateral, poorly defined hypoattenuation mainly involving the subcortical white matter of the occipital lobes | Antihypertensive, anticonvulsant, and steroids | Complete recovery |






