10 June 2026
: Case report 
Management of an 11-cm Femoral Diaphyseal Defect Secondary to Chronic Osteomyelitis Using the Induced Membrane Technique in a 14-Year-Old Girl: A Case Report
Unusual or unexpected effect of treatment
Maojiang Lyu BE 1*, Xin Guo BC 2, Weiji Wang
CD 2, Xiaofeng Zhang DF 1, Zetao Ma AF 3
DOI: 10.12659/AJCR.952628
Am J Case Rep 2026; 27:e952628
Table 1 Serial inflammatory and hematologic laboratory parameters during staged treatment. Leukocyte count, neutrophil percentage, erythrocyte sedimentation rate, hemoglobin, and high-sensitivity (hs) C-reactive protein were recorded at key time points during staged treatment.
| Admission | Before stage 1 | After stage 1 | Early follow-up | Interstage follow-up | Pre-stage 2 | Post-stage 2 | Follow-up | |
|---|---|---|---|---|---|---|---|---|
| Leukocyte count (×10/L) | 8.49 | 5.75 | 10.55 | 7.08 | 6.86 | 5.62 | 10.13 | 8.68 |
| Neutrophils (%) | 60.7 | 70.8 | 74.7 | 64.4 | 62 | 54.3 | 76.6 | 68 |
| ESR (mm/h) | 58 | 58 | 41 | 58 | 44 | 36 | 24 | 53 |
| Hemoglobin (g/L) | 111 | 113 | 63 | 84 | 103 | 106 | 68 | 104 |
| hs-CRP (mg/L) | 18.21 | 22.31 | 66.62 | 19.71 | 4.26 | 3.09 | 87.4 | 12.69 |