06 August 2026
: Case report 
Perioperative Anaphylactic Shock Induced by Cisatracurium: A Case Demonstrating the Diagnostic and Clinical Value of Early Skin Testing
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment, Diagnostic / therapeutic accidents, Unexpected drug reaction, Clinical situation which can not be reproduced for ethical reasons
Yu Ying ABCEF 1, Shenglan Tian ABCDEFG 2, Jingli Chen CD 3, Keding Wang DF 4, Shenghua Li ACDEF 3*DOI: 10.12659/AJCR.952854
Am J Case Rep 2026; 27:e952854
Table 2 Intradermal Test (IDT) agents, concentrations, reactions, and wheal diameters.
| Drug | Test concentration | Reaction | Wheal diameter (mm) |
|---|---|---|---|
| Normal saline (negative control) | — | Negative (−) | 5 |
| Morphine (positive control) | 10 μg/mL | Positive (+, papule enlargement with erythema) | 10 |
| Propofol 1% | 1 mg/mL | Negative (−) | 5 |
| Propofol 2% | 1 mg/mL | Negative (−) | 5 |
| Remimazolam | 10 μg/mL | Negative (−) | 7 |
| Rocuronium | 50 μg/mL | Negative (−) | 5 |
| Sufentanil | 0.5 μg/mL | Negative (−) | 5 |
| Remifentanil | 5 μg/mL | Negative (−) | 5 |
| Dexamethasone | 400 μg/mL | Negative (−) | 7 |
| Palonosetron | 5 μg/mL | Negative (−) | 5 |
| Note: A positive reaction was defined as a wheal ≥ 3 mm larger than the negative control, accompanied by erythema. Testing was performed on postoperative day 6 under standard monitoring conditions. | |||