16 January 2021: Articles
Pancreatic Gastrinoma, Gastrointestinal Stromal Tumor (GIST), Pheochromocytoma, and Hürthle Cell Neoplasm in a Patient with Neurofibromatosis Type 1: A Case Report and Literature Review
Rare coexistence of disease or pathology
Arif A. Arif A , Peter T.W. Kim A , Adrienne Melck A , Andrew Churg A , Zachary Schwartz A , Heather C. Stuart A*DOI: 10.12659/AJCR.927761
Am J Case Rep 2021; 22:e927761
Figure 2. Histopathologic features of GIST, gastrinoma, and pheochromocytoma. Hematoxylin-eosin (H&E) and immunohistochemical staining were performed for c-KIT (CD117) and gastrin. (A) Histological section (H&E) of the jejunal GIST showing tumor cells with a fibrous stromal pattern, inset c-KIT/CD117 staining (acquired 20×); (B) Histological section (H&E) of the neuroendocrine tumor showing sheets of bland cells, inset gastrin staining (acquired 40×); (C) Histopathology (H&E) of pheochromocytoma showing polygonal cells in a nest pattern (acquired 40×), atypical mitosis annotated (yellow); (D) Histopathology (H&E) of pheochromocytoma showing invasion of peri-adrenal adipose tissue invasion (yellow).