06 June 2021: Articles
Ileal Neuroendocrine Tumor in a Patient with Sclerosing Mesenteritis: Which Came First?
Unusual clinical course, Challenging differential diagnosis, Patient complains / malpractice, Rare disease
Cristine Pathirannehalage Don A* , Daniele Sforza A , Leandro Siragusa A , Bruno Sensi A , Matteo Ciancio Manuelli D , Rossana Telesca B , Luca Savino B , Valentina Ferrazzoli B , Simona Grande B , Massimo Villa D , Michele Grande BDOI: 10.12659/AJCR.931372
Am J Case Rep 2021; 22:e931372
Figure 2. Histopathology of well-differentiated neuroendocrine tumor (NET). (A) Hematoxylin and eosin, (B) chromogranin, and (C) synaptofisin staining of a grade 1 ileal NET, showing nests of neuroendocrine cells with round to oval nuclei and “salt and pepper” chromatin. In panel A (original magnification 100×), nuclear staining of Ki67 is only visible in isolated neoplastic cells (Ki67 <3%). A–C, original magnification 20×.