Ileal Neuroendocrine Tumor in a Patient with Sclerosing Mesenteritis: Which Came First?

Cristine Pathirannehalage Don; Daniele Sforza; Leandro Siragusa; Bruno Sensi; Matteo Ciancio Manuelli; Rossana Telesca; Luca Savino; Valentina Ferrazzoli; Simona Grande; Massimo Villa; Michele Grande

doi:10.12659/AJCR.931372

06 June 2021 : Case report Italy

Ileal Neuroendocrine Tumor in a Patient with Sclerosing Mesenteritis: Which Came First?

Unusual clinical course, Challenging differential diagnosis, Patient complains / malpractice, Rare disease

Cristine Pathirannehalage Don^1ABCDEFG*, Daniele Sforza^2ACDEG, Leandro Siragusa^1ABCDEFG, Bruno Sensi^1ABCDEFG, Matteo Ciancio Manuelli^2DG, Rossana Telesca^3BDG, Luca Savino^3BDG, Valentina Ferrazzoli

^4BD, Simona Grande^1BDG, Massimo Villa^2DG, Michele Grande^2BG

DOI: 10.12659/AJCR.931372

Am J Case Rep 2021; 22:e931372

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Figure 2. Histopathology of well-differentiated neuroendocrine tumor (NET). (A) Hematoxylin and eosin, (B) chromogranin, and (C) synaptofisin staining of a grade 1 ileal NET, showing nests of neuroendocrine cells with round to oval nuclei and “salt and pepper” chromatin. In panel A (original magnification 100×), nuclear staining of Ki67 is only visible in isolated neoplastic cells (Ki67 <3%). A–C, original magnification 20×.

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Ileal Neuroendocrine Tumor in a Patient with Sclerosing Mesenteritis: Which Came First?

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