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25 October 2021: Articles

Advanced Leiomyosarcoma of the Retroperitoneal Space in a Kidney Transplant Recipient with a History of Peritoneal Dialysis: A Case Report

Rare disease

Olga Kaźmierczak A* , Anna Kozaczka A , Aureliusz Kolonko B , Maciej Kajor B , Jacek Pająk B , Jerzy Chudek A

DOI: 10.12659/AJCR.933267

Am J Case Rep 2021; 22:e933267

Figure 1. PET-CT with 18F-FDG showing a metabolically active tumor in the left lumbar region of 49×41×44 mm size (A) and numerous liver focal lesions up to 22 mm large (B). The histopathology of the tumor. Hematoxylin-eosin staining ×50 (C) showing metastasis of sarcoma to liver tissue (hepatocytes can be seen in the upper left corner) composed of large atypical, spindle cells with abundant, fibrillary cytoplasm and blunt-ended nuclei forming irregular chaotically arranged cellular fascicles. Immunohistochemical staining ×50 for SMA (D) and desmin (E). In the upper left corner, normal liver tissue can be seen between tumor cells. Tumor cells positively stained for SMA (D) and desmin (E). High-magnification images (×100) of immunohistochemical staining showing sarcoma cells spreading into the normal liver tissue and staining positively for SMA (F) and desmin (G). Ki-67 staining ×100 reflects a high proliferative index in sarcoma cells (H).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923