Figure 2. Patient’s clinical course. On day 1, we performed craniotomy, external decompression, and intracranial monitor insertion for the head injury and fasciotomy and external fixation for the leg injury (emergency surgery). The gray arrow indicates blood transfusion, including 16 units of red cell concentrate, 26 units of fresh frozen plasma, 3 packs of cryoprecipitate, and 10 units of platelet concentrate. The arrowheads indicate the transfusion of VIII/von Willebrand factor (VWF) concentrates (each blank arrowhead indicates 500 units, and each filled arrowhead indicates 2000 units). The lines represent the fibrinogen level (black bold line), platelet count (black line), activated partial thromboplastin time (gray line), and prothrombin time (dotted line). FBG – fibrinogen; PLT – platelet count; APTT – activated partial thromboplastin time; PT – prothrombin time.