Heidenhain Variant of Sporadic Creutzfeldt-Jakob Disease with a Variety of Visual Symptoms: A Case Report with Autopsy Study

Yoshio Hisata; Shun Yamashita; Masaki Tago; Motoi Yoshimura; Tomotaro Nakashima; Tomoyo M. Nishi; Yoshimasa Oda; Hiroyuki Honda; Shu-ichi Yamashita

doi:10.12659/AJCR.938654

11 March 2023 : Case report Japan

Heidenhain Variant of Sporadic Creutzfeldt-Jakob Disease with a Variety of Visual Symptoms: A Case Report with Autopsy Study

Challenging differential diagnosis, Rare disease

Yoshio Hisata^12ABDEF, Shun Yamashita^1ABDEF*, Masaki Tago^1ABDEF, Motoi Yoshimura^3CDF, Tomotaro Nakashima^4ABDF, Tomoyo M. Nishi^1ABF, Yoshimasa Oda^5ABF, Hiroyuki Honda^3CDF, Shu-ichi Yamashita^1DEF

DOI: 10.12659/AJCR.938654

Am J Case Rep 2023; 24:e938654

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Background Case Report Discussion Conclusions References:

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Figure 5. Western blot with frozen specimen of right occipital lobe. (A) Western blot using 3F4 antibody showed the presence of protease-resistant PrP. (B) Western blot using polyclonal antibody specific for (b) type 1 PrPSc and (C) type 2 PrPSc (Tohoku1 and Tohoku2, respectively) showed bands compatible with each antibody.

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Heidenhain Variant of Sporadic Creutzfeldt-Jakob Disease with a Variety of Visual Symptoms: A Case Report with Autopsy Study

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