30 April 2023: Articles
Atypical Hemolytic Uremic Syndrome in a Pregnant Patient with a Thrombomodulin Gene Variant Treated with Plasma Exchange and Eculizumab
Challenging differential diagnosis, Unusual setting of medical care, Rare disease
Lakshmi Kannan A*DOI: 10.12659/AJCR.938896
Am J Case Rep 2023; 24:e938896
Figure 1. (A) Light microscopy H&E staining showing thickened arteriolar walls with onion skinning (arrow) consistent with hypertensive arteriolar nephrosclerosis. (B) H&E staining with higher magnification showing onion skinning of the arteriolar wall with perihilar focal segmental glomerulosclerosis (star). (C) Trichrome stain showing fibrinoid arteriolar necrosis consistent with thrombotic microangiopathy (arrow) with mild interstitial fibrosis and mild tubular atrophy. (D) Showing fibrinoid arteriolar necrosis (arrow).