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30 April 2023 : Case report  USA

Atypical Hemolytic Uremic Syndrome in a Pregnant Patient with a Thrombomodulin Gene Variant Treated with Plasma Exchange and Eculizumab

Challenging differential diagnosis, Unusual setting of medical care, Rare disease

Lakshmi Kannan ORCID logo12ABCDEF*

DOI: 10.12659/AJCR.938896

Am J Case Rep 2023; 24:e938896

Figure 1. (A) Light microscopy H&E staining showing thickened arteriolar walls with onion skinning (arrow) consistent with hypertensive arteriolar nephrosclerosis. (B) H&E staining with higher magnification showing onion skinning of the arteriolar wall with perihilar focal segmental glomerulosclerosis (star). (C) Trichrome stain showing fibrinoid arteriolar necrosis consistent with thrombotic microangiopathy (arrow) with mild interstitial fibrosis and mild tubular atrophy. (D) Showing fibrinoid arteriolar necrosis (arrow).

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923