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20 June 2025 : Case report  Poland

Secondary Pituitary Abscess Inside a Macroadenoma Complicated by Postoperative Hemorrhage and Reinfection: A Case Report

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare coexistence of disease or pathology

Anastasija Krzemińska ORCID logo ABCDEF 1*, Bogdan Czapiga ORCID logo AD 2, Joanna Bladowska ORCID logo CDE 2, Marta Koźba-Gosztyła ORCID logo ADE 1

DOI: 10.12659/AJCR.947794

Am J Case Rep 2025; 26:e947794

Figure 1 (A–F) Preoperative magnetic resonance imaging (MRI) examination of pituitary abscess in the setting of a pituitary adenoma. Transverse unenhanced (A) and coronal T1-weighted images after gadolinium administration (B) show a 30×25×23 mm solid contrast-enhancing sellar mass with expansion into the suprasellar cistern and the sphenoid sinus. The mass compresses the optic chiasm, the bottom of the third ventricle, displaces the pituitary infundibulum and the pituitary gland. The lesion is isodense on T2-weighted dark fluid sequence, except of a hyperintense part measuring 4×4×10 mm in the upper part of the lesion (C). T2-weighted sagittal image shows hypointense mass with a hyperintense part measuring 4×4×10 mm in the upper part of the lesion (D). The DWI sequence showed increased signal within the lesion (E) with features of restricted diffusion on ADC map (F). (G–L) Postoperative computed tomography (CT) and magnetic resonance imaging (MRI) after transnasal resection of pituitary abscess in the setting of a pituitary adenoma. Brain CT examination performed on the day of surgery showed no signs of a residual adenoma (G). The follow-up CT examination performed on the day of readmission to the hospital (H) as well as coronal (I) and sagittal (J) T1-weighted images showed heterogeneous lesion with peripheral enhancement. The DWI sequence revealed increased signal within the lesion (K) with features of restricted diffusion on ADC map (L), which may indicate either hemorrhage or pus.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923