20 January 2026
: Case report
Successful Long-Term Remission in Infantile Acute Leukemia Treated With Chemotherapy and Blinatumomab: A Case Report
Unusual or unexpected effect of treatment
Qiuying He E 1, Bin Zhang A 1, Shuang Li A 1, JiaWei Yang A 1, Liangchun Hao A 1*DOI: 10.12659/AJCR.950502
Am J Case Rep 2026; 27:e950502
Figure 1 There is significant bone marrow growth (magnification 1000×). Anucleate cells to nucleated cells ratio is 1000: 220. The granulocyte series accounts for 1.2%, while the erythroid series accounts for 5.6%. The granulocyte to erythroid ratio is 0.21: 1. The granulocyte series exhibits drastically decreased proliferation. Red cell series hyperplasia has diminished, and no noticeable morphological abnormalities have been found. The lymphoid system exhibited aberrant hyperplasia, with big cells (91.2%) in round or oval shape with uneven borders. The cytoplasm was sparse and sky-blue. The nuclei were distorted, displaying obvious pits, folds, and indentations. The nuclear chromatin was sparse and fine-grained, with 1 to 3 nucleoli visible in certain cells. The bone marrow smear contained 25 megakaryocytes. There were no typical megakaryocytes forming plates throughout the smear. Small clusters of platelets were occasionally seen.






