19 December 2025
: Case report 
Primary Orbital Lymphoma Manifesting as Increased Intraocular Pressure: A Case Report
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment
Miaomiao Sun AEG 1, Zhaohui Xiong F 1, Yincong Xu B 1, Zhongyou Zhou F 1, Jiale Wu BC 1, Jiangzhou Han BC 1, Lina Zhao A 1*DOI: 10.12659/AJCR.951048
Am J Case Rep 2025; 26:e951048
Figure 1 (A) The patient’s ocular condition at admission. The right eye appeared essentially normal; the left eye demonstrated severe eyelid swelling, increased skin tension, and rigidity of the skin and subcutaneous tissues, preventing voluntary eye opening. Ocular motility was completely restricted and fixed. (B) After chemoradiotherapy, there was a substantial reduction in eyelid edema within the left eye, as well as pronounced improvement in skin tension. The patient was able to open the eye with assistance.