15 May 2026
: Case report 
A 56-Year-Old Woman With Systemic Lupus Erythematosus on Trimethoprim-Sulfamethoxazole Prophylaxis Presenting With Breakthrough Nocardiosis
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment
Ming Lu BCE 1,2, Jingwen Zhang BCF 3,4, Ying Liu CD 5, Feng Nie BC 6,4, Tianyu Zou BC 1,4, Haijun Li CD 7, Ping Li ABEG 1,2*, Tianxin Xiang ABEF 2,6DOI: 10.12659/AJCR.952006
Am J Case Rep 2026; 27:e952006
Figure 1 Initial computed tomography scan findings (November 4, 2024). The scans reveal the emergence of a newly developed high-density consolidation in the right upper lobe. Following these findings, empirical treatment with intravenous ceftazidime (2 g twice daily) was initiated, while fluconazole (400 mg daily) administration was continued. (A) Lung window view; (B) mediastinal window view.