15 May 2026
: Case report
A 56-Year-Old Woman With Systemic Lupus Erythematosus on Trimethoprim-Sulfamethoxazole Prophylaxis Presenting With Breakthrough Nocardiosis
Unusual clinical course, Challenging differential diagnosis, Unusual or unexpected effect of treatment
Ming Lu BCE 1,2, Jingwen Zhang BCF 3,4, Ying Liu CD 5, Feng Nie BC 6,4, Tianyu Zou BC 1,4, Haijun Li CD 7, Ping Li ABEG 1,2*, Tianxin Xiang ABEF 2,6DOI: 10.12659/AJCR.952006
Am J Case Rep 2026; 27:e952006
Figure 2 Follow-up chest computed tomography scan after 1 month of voriconazole therapy (December 4, 2024). (A–C) Lung window images demonstrate progression of the consolidation in the right upper lobe compared to prior scans, with an increase in size and density. (D–F) Corresponding mediastinal window images for the lung window images presented in (A–C).






