21 September 2026
: Case report
Simultaneous Thyroid Eye Disease and IgG4-Related Orbital Disease in a Patient With Diabetes Mellitus: A Case Report
Challenging differential diagnosis, Diagnostic / therapeutic accidents, Management of emergency care, Educational Purpose (only if useful for a systematic review or synthesis), Rare coexistence of disease or pathology
Brenda Hayatulhaya ABCDEF 1*, Tomoyuki Kashima ABCDEFG 2DOI: 10.12659/AJCR.952068
Am J Case Rep 2026; 27:e952068
Figure 6 Immunohistochemical staining for IgG4 revealing a markedly increased number of IgG4-positive plasma cells (original magnification ×100). Quantitative assessment showed > 50 IgG4-positive plasma cells per high-power field with an IgG4/IgG ratio > 40%, supporting the diagnosis of IgG4-related disease.






