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12 May 2026 : Case report  China

Sleeve Resection of the Right Upper Lobe for Tracheobronchial Metastasis of Hepatocellular Carcinoma With Superior Vena Cava Involvement: A Case Report and Literature Review

Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare disease

Peng Cao ABEF 1,2, Yulin Wang BCDF 1,3, Qing Wang ABCD 1, Wei Cai ABE 1,4, Rui Zhang ORCID logo DG 2, Zhigang Li ABCDG 1*, Junfeng Geng ABCDEFG 1

DOI: 10.12659/AJCR.952125

Am J Case Rep 2026; 27:e952125

Figure 1 Preoperative evaluation and intraoperative findings of a patient with endobronchial metastasis from hepatocellular carcinoma. (A) March 2025 PET-CT Findings: Right hilar mass, dimensions: 3.1×2.8 cm; FDG-avid lesion (SUVmax 10.3), obstructive pneumonitis in right upper lobe. The highlighted hyperintense regions (orange) demonstrate the tumor. (B) Bronchoscopy identified complete tumor occlusion at the right upper lobe bronchus ostium. (C) June 2025 follow-up imaging: contrast-enhanced chest CT demonstrated progressive disease with interval enlargement of the right hilar mass to 6.1 cm maximal diameter (3 weeks after neoadjuvant therapy initiation). (D) Green solid line: outlines the anatomical contour of the SVC, clearly illustrating its relationship to the tumor. The red circle indicates the most prominent site of SVC invasion by the tumor, representing a critical surgical challenge for vascular dissection and preservation. Black dashed line: denotes the pericardial incision, exposing the intrapericardial root of the SVC. Yellow contour: highlights the use of a suction device to retract the SVC, revealing the underlying main trunk of the right pulmonary artery and demonstrating the difficulty in dissecting the proximal pulmonary artery. PET – positron emission tomography; CT – computed tomography; FDG – fluorodeoxyglucose; SUVmax – standardized uptake value-maximum; SVC – superior vena cava.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923