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16 May 2026 : Case report  Japan

Long-Term Response to Pembrolizumab in Metastatic Metaplastic Breast Carcinoma: A Case Report

Unusual clinical course, Unusual or unexpected effect of treatment

Yuki Oshima ABCDEF 1, Takamasa Suzuki D 1, Yumi Fukaya D 1, Keiko Hosoya D 1, Yuko Tanaka D 1, Makoto Wakahara ABCDEF 1*, Yoshihisa Umekita CD 2, Yugo Tanaka ABCDEF 1

DOI: 10.12659/AJCR.952330

Am J Case Rep 2026; 27:e952330

Figure 5 Radiographic imaging. Horizontal computed tomography section showing (A) development of sternal metastasis (left) and multiple lung metastases (middle and right) upon recurrence. (B) One month after receiving pembrolizumab, gemcitabine, and carboplatin, sternal mass (left) and bilateral lung metastases (middle and right) indicating pseudo-progression. (C) Thirty months after chemoimmunotherapy initiation, the metastatic lesions shrank significantly. Lesions are indicated by red arrows.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923