24 August 2026
: Case report 
Ovarian Lymphoma and Bone Metastasis Presenting With Paraparesis in an Adolescent: A Case Report
Challenging differential diagnosis, Rare disease
Ryan Haryana Darajatun CDEF 1*, Aditiyono AB 2, Siti Salima
ABCDEFG 1
DOI: 10.12659/AJCR.952834
Am J Case Rep 2026; 27:e952834
Figure 5 Immunohistochemical examination. (A) Hematoxylin and eosin staining demonstrating diffuse proliferation of large atypical lymphoid cells, consistent with diffuse large B-cell lymphoma. (B) CD20 immunohistochemical staining showing strong diffuse membranous positivity in neoplastic lymphoid cells, confirming B-cell lineage. (C) Ki-67 immunohistochemical staining demonstrating a high proliferative index (approximately 80%) within the tumor cell population. (D) CD3 immunohistochemical staining showing negative staining in neoplastic cells, supporting exclusion of T-cell lymphoma.