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13 August 2026 : Case report  USA

Delayed-Onset Giant Bleb Formation and Persistent Intraocular Pressure Elevation in a Patient With COVID-19 and a Long-Term Ahmed Glaucoma Valve

Unusual clinical course, Diagnostic / therapeutic accidents

Elizabeth Sun ORCID logo ABDEF 1, Andrew G. Iwach DE 2,3, Shan C. Lin ABDE 2,3*

DOI: 10.12659/AJCR.953273

Am J Case Rep 2026; 27:e953273

Figure 1 Slit-lamp photographs and intraocular pressure (IOP) measurements of the left eye (OS) from initial presentation through 2 months after initiation of medical therapy(A) At initial presentation, an enlarged superotemporal bleb overlying the Ahmed plate (white arrow) was observed, with an IOP of 50 mm Hg. The bleb appeared distended and fluid-filled, causing distortion of the upper eyelid. (B) After 1 day of medical therapy, IOP decreased to 19 mm Hg. The bleb remained enlarged with persistent upper eyelid distortion; however, its firmness and degree of protrusion were reduced relative to those at presentation. (C) After 5 days of medical therapy, IOP further decreased to 14 mm Hg. The bleb remained mildly distended, with continued reduction in size and less upper eyelid distortion. (D) After 19 days of medical therapy, IOP decreased to 9 mm Hg. The bleb returned to its baseline appearance. (E) After 1 month of medical therapy, IOP stabilized at 17 mm Hg. The bleb maintained a normal appearance, with mild erythema of the overlying conjunctiva. (F) After 2 months of medical therapy, IOP remained stable at 17 mm Hg. The bleb maintained a normal appearance, with mild residual localized erythema.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923