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05 July 2020 : Case report  USA

Coccidioidomycosis and Pulmonary Emboli: A Report of 5 Cases

Challenging differential diagnosis, Management of emergency care, Rare coexistence of disease or pathology

John G. Prichard1BEF*, Michelle B. Azimov23BEF, Karlos Z. Oregel2BE

DOI: 10.12659/AJCR.924179

Am J Case Rep 2020; 21:e924179

Table 1. Tabular summary of 5 cases of coccidioidomycosis with pulmonary emboli.

CaseAgeSexEthnicityLocation of infectionComplement fixation titer at diagnosisCocci treatmentPulmonary emboli (PE) locationVTE treatmentVTE risk factors
137FLatinoPneumonia (LLL)1: 16Anti-fungalBilateral lower lobe and RML of lungDOACCardiolipin antibodies positive; obesity; travel prior to PE
263MLatinoPneumonia (LLL)1: 32NoneSaddle EmboliDOACTransient positive anticardiolipin antibodies; obesity; splenectomy
342FLatinoPneumonia (RUL)1: 2Anti-fungalRLL of lungDOACNegative hypercoagulable evaluation
445MLatinoCNS (basilar cisterns), pneumonia, skin1: 64Anti-fungalLLL, RLL, RML, RUL of lungDOACRecent hospitalization (2 weeks after cocci diagnosis)
535MLatinoPneumonia (RUL, RML, RLL)1: 32Anti-fungalLLL of lungDOACTibial and left peroneal veins DVT; obesity
Cocci – Coccidioidomycosis; VTE – venous thromboembolism; LLL – left lower lobe; DOAC – direct acting oral anticoagulant; RUL – right upper lobe; RLL – right lower lobe; CNS – central nervous system; RML – right middle lobe; DVT – deep vein thrombosis.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923