26 November 2020
: Case report 
A Case Report of Malignant Eccrine Porocarcinoma Involving the Palm Requiring Surgical Excision and Free Flap Reconstruction
Challenging differential diagnosis, Unusual or unexpected effect of treatment, Rare coexistence of disease or pathology
Kevin L. Chow1ABCDEF, Xane Peters1CDEF, Hassan Mashbari2ABCDEF*, Mohammad Shokouh-Amiri1CDEF, Martin Benjamin1ABCDEF, Michael Warso1ACDEDOI: 10.12659/AJCR.925231
Am J Case Rep 2020; 21:e925231
Table 1. Tumor markers.
| Immunohistochemical marker | Porocarcinoma staining result | Typical basal cell carcinoma | Typical squamous cell carcinoma | Typical melanoma |
|---|---|---|---|---|
| CEA | Positive | Negative | Negative | Positive |
| CKAE1/3 | Positive | Positive | Positive | Negative |
| Cam5.2 | Positive | Positive | Negative | Negative |
| CK5/6 | Positive | Positive | Positive | Negative |
| CK7 | Positive | Positive | Negative | Negative |
| CK19 | Positive | Positive | Positive | Negative |
| EMA | Positive | Negative | Positive | Positive |
| p63 | Positive | Positive | Positive | Negative |
| S100 | Negative | Negative | Negative | Positive |
| CK20 | Negative | Negative | Negative | Negative |
| CD31 | Negative | Negative | Negative | Negative |
| Chromogranin | Negative | Negative | Negative | Negative |
| Her-2/Neu | Negative | Negative | Negative | Negative |
| Melan A | Negative | Negative | Negative | Positive |
| Synaptophysin | Negative | Negative | Negative | Negative |