25 July 2020
: Case report 
Unusual Early Recovery of a Critical COVID-19 Patient After Administration of Intravenous Vitamin C
Unusual clinical course, Unusual or unexpected effect of treatment
Hafiz Muhammad Waqas Khan1ABEF*, Niraj Parikh2AF, Shady Maher Megala3AF, George Silviu Predeteanu1AEFDOI: 10.12659/AJCR.925521
Am J Case Rep 2020; 21:e925521
Table 1. Laboratory data showing various markers and their trends on hospital days 1, 6, 10, and 16.
| Measure | Reference range | Day 1 | Day 6 | Day 10 | Day 16 |
|---|---|---|---|---|---|
| White cell count | 4.5–11×10/µL | 8.60 | 6.97 | 5.93 | 4.75 |
| Red cell count | 4.25–5.49×10/µL | 3.36 | 3.22 | 3.05 | 3.03 |
| Hemoglobin | 12–15.7 g/dL | 9.5 | 9.0L | 8.3 | 8.3 |
| Hematocrit | 34.9–46.9% | 30.2 | 29.8 | 27.7 | 27.3 |
| Platelet count | 140–440×10/µL | 323 | 322 | 346 | 379 |
| Glucose | 70–105 mg/dL | 116 | 94 | 106 | 100 |
| Blood urea nitrogen | 7–22 mg/dL | 15 | 31 | 17 | 9 |
| Serum creatinine | 0.5–1.5 mg/dL | 0.77 | 1.16 | 0.66 | 0.63 |
| Sodium | 134–145 mmol/L | 132 | 140 | 142 | 138 |
| Potassium | 3.5–5.1 mmol/L | 3.2 | 4.4 | 3.8 | 4.0 |
| Chloride | 98–112 mmol/L | 94 | 101 | 103 | 104 |
| Carbon dioxide | 24–30 mmol/liter | 26 | 29 | 26 | 28 |
| pH arterial | 7.35–7.45 | 7.465 | 7.355 | 7.493 | – |
| pCO arterial | 35–45 mmHg | 44.6 | 52.1 | 40.2 | – |
| pO arterial | 80–100 mmHg | 94.7 | 167.7 | 77.1 | – |
| Bicarbonate arterial | 22–26 mmol/L | 31.4 | 30.4 | 30.2 | – |
| Total protein | 6–8 g/dL | – | 7.4 | – | – |
| Albumin | 3.5–5.0 g/dL | – | 1.9 | – | – |
| Total bilirubin | 0.2–1.3 mg/dL | – | 0.5 | – | – |
| Alanine aminotransferase | 7–56 U/L | – | 18 | – | – |
| Aspartate aminotransferase | 8–40 U/L | – | 37 | – | – |
| Alkaline phosphatase | 39–117 U/L | – | 106 | – | – |
| Total creatine kinase | 35–230 U/L | – | 50 | – | – |
| Ferritin | 10–291 ng/mL | – | 767.2 | – | – |
| Fibrinogen | 200–400 mg/dL | – | 488 | – | – |
| Venous lactic acid | 0.5–2.0 mmol/L | – | 1.3 | – | – |
| Lactate dehydrogenase | 100–225 U/L | – | 312 | – | – |
| Procalcitonin | 0.02–0.09 ng/mL | – | 0.06 | – | – |
| Interleukin-6 | <5 pg/mL | – | 52 | – | – |
| Prothrombin time | 9.5–12 seconds | 10.2 | – | – | – |
| International normalized ratio | 0.88–1.11 | 0.99 | – | – | – |
| Partial thromboplastin time | 23–31 seconds | 27.3 |