28 October 2020
: Case report 
Suspected Levetiracetam-Induced Rhabdomyolysis: A Case Report and Literature Review
Unusual or unexpected effect of treatment, Unexpected drug reaction
Imran A. Moinuddin12BEF*DOI: 10.12659/AJCR.926064
Am J Case Rep 2020; 21:e926064
Table 1. Data of reported cases of levetiracetam-induced rhabdomyolysis.
| Reference | Year | Patient | Acute kidney injury | Myalgias | Peak CK (IU/L) | Time to peak CK | |
|---|---|---|---|---|---|---|---|
| Age (years) | Sex | ||||||
| Thomas et al. []12 | 2019 | 62 | M | No | No | 19 000 | 5 days |
| Rastogi et al. []13 | 2018 | 42 | M | Yes | Unknown | 30 000 | 3 days |
| Mena-Martin et al. []20 | 2018 | 28 | M | Yes | No | 1559 | 7 days |
| Kubota et al. []21 | 2017 | 26 | F | No | Yes | 4396 | 15 days |
| Sohn et al. []22 | 2017 | 40 | M | No | Yes | 7800 | 6 days |
| Di Lorenzo and Li []14 | 2017 | 27 | M | NR | No | 49 539 | 5 days |
| Shahbaz et al. []23 | 2016 | 43 | M | No | No | 29 750 | 7 days |
| Singh et al. []15 | 2016 | 16 | M | Yes | Yes | 15 111 | 4 days |
| Ramon et al. []16 | 2016 | 25 | M | No | Unknown | 15 811 | 4 days |
| Sivasambu and Yogarajah []17 | 2015 | 30 | M | NR | No | 37 622 | 4 days |
| Akiyama et al. []6 | 2014 | 29 | F | NR | Yes | 2410 | 4 days |
| Isaacson et al. []24 | 2014 | 19 | M | Yes | No | 29 136 | 8 days |
| Spengler et al. []18 | 2014 | 23 | F | Yes | Yes | 1368 | 4 days |
| NR – not reported; CK – creatine kinase. | |||||||