A 31-Year-Old Man with COVID-19-Associated Empyema and Lupus Anticoagulant

18 August 2020: Articles

Unknown etiology, Unusual clinical course, Challenging differential diagnosis, Diagnostic / therapeutic accidents, Unusual setting of medical care

Keerthi Yarlagadda ^A* , Kaihong Mi ^A , Selin Sendil ^E , Connie L. Koons ^E , Saketram Komanduri ^E , John T. Cinicola ^A

DOI: 10.12659/AJCR.926623

Am J Case Rep 2020; 21:e926623

Table 1. Results of hematology workup.

Parameter	Value	Reference range
Prothrombin time (PT)	27.7 seconds	9.4–12.5
International Normalized Ratio	2.4	0.8–1.1
Activated Partial Thromboplastin Time (APTT)	47.2 seconds	25.1–36.5
PTT LA (Partial Thromboplastin Time Lupus Anticoagulant) mixing	75 seconds	≤40
Immediate PTT-LA mix	Not corrected
Immediate PT mix	10.8 seconds	≤11.5
Platelet count	420 K/uL	140–366
D-dimer	2590 FFEU/mL	0–499
Fibrinogen	590 MG/DL	200–393
Factor VII	45	60–150%
Factor VIII	302	50–180%
Factor XII	48	50–150%
B2- Glycoprotein I IgG Ab		≤20 SGU
B2- Glycoprotein I IgM Ab		≤20 SMU
B2-Glycoprotein I IgA Ab		≤20 SAU
Lupus Anticoagulant	Detected
Anti-Cardiolipin IgG		≤14 GPL
Anti-Cardiolipin IgM	45	≤12 MPL
Anti-Nuclear Antibody	Negative