15 August 2020
: Case report 
A 57-Year-Old African American Man with Severe COVID-19 Pneumonia Who Responded to Supportive Photobiomodulation Therapy (PBMT): First Use of PBMT in COVID-19
Unusual or unexpected effect of treatment
Scott A. Sigman1ABCDEF*, Soheila Mokmeli2ABCDEF, Monica Monici3A, Mariana A. Vetrici4BCDEFDOI: 10.12659/AJCR.926779
Am J Case Rep 2020; 21:e926779
Table 2. Evaluation criteria before and after photobiomodulation therapy in a COVID-19 patient.
| Parameters | Before treatment | After treatment | Normal range or evaluation criteria |
|---|---|---|---|
| PSI | Class V (142) | Class II (67) | Risk Class (Points): DispositionClass I (<50): OutpatientClass II (51–70): OutpatientClass III (71–90): Outpatient/brief InpatientClass IV (91–130): InpatientClass V (>130): Inpatient |
| SMART-COP | 5 | 2 | 0 points: Very low risk of needing IRVS1 point: Low risk (1 in 20) of needing IRVS2 points: Moderate risk (1 in 10) of needing IRVS3 points: High risk (1 in 6) of needing IRVS≥4 points: High risk (1 in 3) of needing IRVS; Consider ICU admission |
| Brescia-COVID | 4 | 0 | 0 – monitor1 – add O and monitor2 – CXR, ABG, O therapy, monitor>2 – HFNC and reassess. If still >2, intubate. |
| CAP total | 36.68 | 82.82 | Calculated based on (CAP) score questionnaire: 75–100% |
| CAP respiratory | 67.52 | 87.17 | 75–100% |
| CAP well-being | 0.0 | 73.07 | 75–100% |
| RALE | 8 | 5 | Lungs score dependent on extent of involvement based on consolidation or ground-glass opacities for each lung, total score is the sum of the score of the lungs: 0 – no involvement; 1 – <25% of lung involved; 2 – 25–50% of lung involved; 3 – 50–75% of lung involved; 4 – >75% of lung involved. |
| WBC | 10.7 | 6.5 | 4.5–11 |
| CRP | 15.1 | 1.23 | 3 mg/mL |
| O Requirement | 2–3 L/min | 1 L/min | 0 L/min |
| SpO | 93–94% | 100% | ≥94% |
| PSI – Pneumonia Severity Index; SMART-COP – Systolic blood pressure, Multilobar infiltrates, Albumin, Respiratory rate, Tachycardia, Confusion, Oxygen, and pH; CAP – Community-Acquired Pneumonia; RALE – Radiographic Assessment of Lung Edema; SpO – Oxygen saturation; WBC – White Blood Cells; CRP – C-Reactive Protein; IRVS – Intensive Respiratory or Vasopressor Support; CXR – Chest x-ray; ABG – Arterial Blood Gas; HFNC – High-Flow Nasal Cannula. | |||