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24 November 2020: Articles

A 45-Year-Old Man with Scleroderma Renal Crisis Associated with a History of Systemic Sclerosis Sine Scleroderma

Challenging differential diagnosis, Unusual setting of medical care, Rare disease

Panupong Hansrivijit A* , Kelechi F. Omeonu B , Halimat O. Lawal B , Mounika Gangireddy B , Kinjal P. Gadhiya B , Ravinder S. Dhatt B

DOI: 10.12659/AJCR.927030

Am J Case Rep 2020; 21:e927030

Table 3. Etiologies of thrombotic microangiopathy.

EtiologiesExample
HematologicDIC
STEC-HUS
PNC-HUS
TTP
InfectionHIV
Others
Auto-immuneSLE
Antiphospholipid
SRC
GlomerularIgA nephropathy
ANCA-GN
FSGS
MN
MPGN/C3G
TransplantBMT
SOT
Severe hypertension
Malignancy
Pregnancy
HereditaryMMACHC gene
DGKE gene
INF2 gene
Drug-inducedQuinine
CNIs
Sirolimus
Interferons
VEGF inhibitors
Chemotherapy
Cocaine
Ticlopidine
ANCA-GN – antineutrophil cytoplasmic antibody-mediated glomerulonephritis; BMT – bone marrow transplant; CNI – calcineurin inhibitors; DIC – disseminated intravascular coagulation; FSGS – focal segmental glomerulosclerosis; HIV – human immunodeficiency virus; MN – membranous nephropathy; MPGN/C3G – membranoproliferative glomerulonephritis/C3 glomerulopathy; PNC-HUS – pneumococcal hemolytic uremic syndrome; SLE – systemic lupus erythematosus; SOT – solid-organ transplant; SRC – scleroderma renal crisis; STEC-HUS – shiga-toxin producing -hemolytic uremic syndrome; TTP – thrombotic thrombocytopenic purpura.
* e.g. cyclosporine, tacrolimus;
** e.g. bevacizumab, sunitinib;
*** e.g. gemcitabine, mitomycin.

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American Journal of Case Reports eISSN: 1941-5923
American Journal of Case Reports eISSN: 1941-5923