08 March 2021>: Articles
Diagnosis of GATA2 Deficiency in a Young Woman with Hemophagocytic Lymphohistiocytosis Triggered by Acute Systemic Cytomegalovirus Infection
Challenging differential diagnosis, Rare disease
Nicole Burak E* , Naveed Jan E , Jason Kessler E , Erwin Oei E , Priya Patel E , Scott Feldman EDOI: 10.12659/AJCR.927087
Am J Case Rep 2021; 22:e927087
Table 1. Flow cytometric screening of lymphocyte subsets for primary immunodeficiency. The results revealed low levels of B, CD4s, and natural killer cells.
Lymphocyte subsets | Value | Reference range |
---|---|---|
% CD3 | 96 (H) | 62–87% |
Absolute CD3 | 367 (L) | 570–2400 cells/uL |
% CD4 | 21 (L) | 32–64% |
Absolute CD4 | 79 (L) | 430–1800 cells/uL |
% CD8 | 78 (H) | 15–46% |
Absolute CD8 | 296 | 210–1200 cells/uL |
CD4: CD8 ratio | 0.27 (L) | 0.8–3.90 ratio |
% CD19 | 2 (L) | 6–23% |
Absolute CD19 | 8 (L) | 91–610 cells/uL |
% CD45RA | 30 | 28–71% |
Absolute CD45RA | 25 (L) | 150–870 cells/uL |
% CD45RO | 69 | 28–72% |
Absolute CD45RO | 56 (L) | 190–1050 cells/uL |
% Natural killer cells | 4–26% | |
Absolute atural killer cells | 78–470 cells/uL |